Polyclonal Population Structure of Streptococcus pneumoniae Isolates in Spain Carrying mef and mef plus erm (B)
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چکیده
منابع مشابه
Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B).
The population structure (serotypes, pulsed-field gel electrophoresis [PFGE] types, and multilocus sequencing types) of 45 mef-positive Streptococcus pneumoniae isolates [carrying mef alone (n = 17) or with the erm(B) gene n = 28)] were studied. They were selected from among all erythromycin-resistant isolates (n = 244) obtained from a collection of 712 isolates recovered from different Spanish...
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1 Servicio de Microbiología. Hospital Universitario Ramón y Cajal, and CIBER-ESP, 9 Madrid, Spain; 2 Institute for Medical Microbiology, National Reference Center for 10 Streptococci, University Hospital (RWTH), Aachen, Germany. 11 12 13 Running title: Polyclonal mef positive Spanish S. pneumoniae isolates 14 15
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One hundred and twenty-four erythromycin-resistant pneumococcal isolates were examined for the presence of macrolide resistance genes. The erm(B) gene was detected in 118 (95.2%) isolates and the mef(A) gene in 83 (66.9%) isolates. Both the mef(A) and erm(B) genes were detected in 77 (62.1%) isolates. DNA macrorestriction analysis of these isolates identified them as belonging to a single multi...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 2008
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.01487-07